Bacterial Meningitis in Aging Adults

Dexamethasone in Adults with Bacterial Meningitis

Cognitive outcome in adults after bacterial meningitis.

OBJECTIVE To evaluate cognitive outcome in adult survivors of bacterial meningitis. METHODS Data from three prospective multicentre studies were pooled and reanalysed, involving 155 adults surviving bacterial meningitis (79 after pneumococcal and 76 after meningococcal meningitis) and 72 healthy controls. RESULTS Cognitive impairment was found in 32% of patients and this proportion was simi...

Dexamethasone in adults with bacterial meningitis.

BACKGROUND Mortality and morbidity rates are high among adults with acute bacterial meningitis, especially those with pneumococcal meningitis. In studies of bacterial meningitis in animals, adjuvant treatment with corticosteroids has beneficial effects. METHODS We conducted a prospective, randomized, double-blind, multicenter trial of adjuvant treatment with dexamethasone, as compared with pl...

Endocarditis in adults with bacterial meningitis.

BACKGROUND Endocarditis may precede or complicate bacterial meningitis, but the incidence and impact of endocarditis in bacterial meningitis are unknown. METHODS AND RESULTS We assessed the incidence and clinical characteristics of patients with meningitis and endocarditis from a nationwide cohort study of adults with community-acquired bacterial meningitis in the Netherlands from 2006 to 201...

Community-acquired bacterial meningitis in adults.

We reviewed the charts of all patients > or = 15 years of age or older in whom community acquired-bacterial meningitis was diagnosed at Srinagarind Hospital, Khon Kaen, Thailand from 1984 through 1998. Eighty-five patients were included in this study. The clinical manifestation was acute meningitis with CSF neutrophilic pleocytosis and low glucose content. Gram's staining of CSF was positive in...